Found 12 matching trials
To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers PHASE1 Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
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Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, Phaseâ
Ą, Double-Blinded, Placebo-Controlled Study PHASE2 This is a phase II, multicenter, randomised, parallel, double-blind, placeb...
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Multiple Locations
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Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC PHASE3 The purpose of this study is to assess the efficacy of selumetinib in combi...
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Active Not Recruiting
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Fulvestrant With or Without AZD6244 in Treating Patients With Advanced Breast Cancer That Progressed After Aromatase Inhibitor Therapy PHASE2 RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone th...
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Universitair Ziekenhuis Gent
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Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment. PHASE2 The purpose of this study is to treat patients with locally advanced or met...
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Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer PHASE2 This phase II trial studies how well iodine I-131 works with or without sel...
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UC San Diego Moores Cancer Center
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Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT) PHASE3 Selumetinib therapy in patients with metastatic uveal melanoma....
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Comparing Complete Remission After Treatment With Selumetinib/Placebo in Patient With Differentiated Thyroid Cancer PHASE3 The study is designed to evaluate the clinical efficacy, safety and tolerab...
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AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients PHASE2 The purpose of this study is to compare the efficacy of AZD6244 in combinat...
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Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients PHASE2 To assess the efficacy in terms of overall survival of AZD6244 in combinati...
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